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1.
Rev. bras. enferm ; 76(3): e20220606, 2023. tab
Artigo em Inglês | LILACS-Express | LILACS, BDENF | ID: biblio-1514993

RESUMO

ABSTRACT Objectives: to identify factors associated with older adults' knowledge, attitude and practice regarding skin cancer prevention. Methods: this is a cross-sectional study, carried out with 120 older adults from a Basic Health Unit in Quixadá, Ceará, from September to November 2018. Results: individuals aged 60 to 69 years and working were statistically associated with adequate knowledge (p=0.038). Having light skin, eyes and hair was associated with adequate attitude (p=0.030). Having skin problems, such as bleeding wounds, was associated with adequate practice (p=0.016). With regard to inappropriate behavior for skin cancer prevention, there was a statistically significant association between working or having worked under direct exposure to the sun, inadequate knowledge (p=0.036), inadequate attitude (p=0.010) and having incomplete primary education and inadequate practice (p<0.001). Conclusions: sociodemographic and clinical factors influence older adults' knowledge, attitude and practice regarding skin cancer prevention.


RESUMEN Objetivos: identificar factores asociados al conocimiento, actitud y práctica de los ancianos en relación a la prevención del cáncer de piel. Métodos: estudio transversal, realizado con 120 ancianos de una Unidad Básica de Salud de Quixadá, Ceará, de septiembre a noviembre de 2018. Resultados: los individuos de 60 a 69 años y que trabajaban se asociaron estadísticamente con conocimientos adecuados (p=0,038). Tener piel, ojos y cabello claros se asoció con una actitud adecuada (p=0,030). Tener problemas en la piel, como heridas sangrantes, se asoció con una práctica adecuada (p=0,016). Sobre conductas inapropiadas para la prevención del cáncer de piel, hubo asociación estadísticamente significativa entre trabajar o haber trabajado bajo exposición directa al sol, conocimientos inadecuados (p=0,036), actitud inadecuada (p=0,010), tener instrucción primaria incompleta y práctica inadecuada (p<0,001). Conclusiones: los factores sociodemográficos y clínicos influyen en el conocimiento, la actitud y la práctica de los ancianos respecto a la prevención del cáncer de piel.


RESUMO Objetivos: identificar fatores associados a conhecimento, atitude e prática de idosos sobre a prevenção do câncer de pele. Métodos: estudo transversal, realizado com 120 idosos de uma Unidade Básica de Saúde em Quixadá, Ceará, de setembro a novembro de 2018. Resultados: indivíduos na faixa etária de 60 a 69 anos e trabalhando estiveram associados estatisticamente ao conhecimento adequado (p=0,038). O fato de ter pele, olhos e cabelos claros estava associado à atitude adequada (p=0,030). Ter problemas de pele, do tipo ferida sangrante, estava associado à prática adequada (p=0,016). Acerca das condutas inadequadas para a prevenção do câncer de pele, observou-se associação estatisticamente significante entre trabalhar ou já ter trabalhado sob exposição direta ao sol, conhecimento inadequado (p=0,036), atitude inadequada (p=0,010), ter o ensino fundamental incompleto e prática inadequada (p<0,001). Conclusões: fatores sociodemográficos e clínicos influenciam no conhecimento, atitude e prática de idosos sobre a prevenção do câncer de pele.

2.
J. vasc. bras ; 22: e20220062, 2023. graf
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1448593

RESUMO

Resumo A fístula arteriovenosa (FAV) é o principal acesso para hemodiálise devido à sua patência superior e menores índices de complicação quando comparada aos demais acessos para hemodiálise. Relatamos o caso de uma paciente do sexo feminino, de 69 anos, com doença renal crônica dialítica secundária a nefroesclerose hipertensiva com FAV radio-cefálica no membro superior esquerdo realizada há 9 anos. Há 2 anos, foi submetida a transplante renal e fazia uso de imunossupressores. Evoluiu com aparecimento de lesão crostosa em antebraço esquerdo há 3 meses, foi submetida a biópsia excisional, e foi evidenciado carcinoma espinocelular bem diferenciado e superficialmente invasivo, com margens cirúrgicas laterais e profundas livres de neoplasia. No seguimento de 1 ano, a paciente não apresentava sinais de recidiva neoplásica.


Abstract The main type of access used for hemodialysis is the arteriovenous fistula (AVF) because it offers superior patency and lower complication rates when compared to other hemodialysis accesses. We report the case of a 69-year-old female patient with chronic kidney disease on dialysis secondary to hypertensive nephrosclerosis with a radiocephalic AVF in the left upper limb created 9 years previously. Two years previously, she had undergone a kidney transplant and was taking immunosuppressants. A crusted lesion developed on her left forearm with onset 3 months before presentation and she underwent an excisional biopsy that revealed a well-differentiated and superficially invasive squamous cell carcinoma, with lateral and deep surgical margins free from neoplasia. At 1-year follow-up, the patient showed no signs of neoplastic recurrence.

3.
Rev. bras. oftalmol ; 81: e0055, 2022. tab, graf
Artigo em Português | LILACS | ID: biblio-1394862

RESUMO

RESUMO Objetivo Analisar o perfil clínico de pacientes portadores de neoplasias escamosas da superfície ocular. Métodos Foram avaliados os principais fatores de risco envolvidos na gênese das neoplasias escamosas da superfície ocular, as características clínicas dos pacientes e os hábitos comportamentais associados. Foram incluídos neste trabalho de coorte histórica 80 pacientes com diagnóstico anatomopatológico de neoplasia escamosa da superfície ocular atendidos entre os anos de 2010 e 2020 em um hospital referência em oculoplástica e segmento anterior de Santa Catarina. Os dados clínicos e desfechos foram avaliados por meio da análise de prontuário e entrevista, sendo posteriormente tabulados no Excel e submetidos à analise estatística por meio do software Statistical Pakage for the Social Sciences, versão 16. Resultados Foi observado que 73,8% (n=59) eram do sexo masculino. A média de idade da amostra foi de 62 anos. Quanto ao fototipo de pele, de acordo com a escala de Fitzpatrick, constatou-se que a maioria apresentou os fototipos 1 e 2 (22; 27,5% e 44; 55%, respectivamente). Em relação à exposição ocupacional ao sol/radiação, 48% (n=60) apresentaram história de exposição ocupacional, sendo que, destes, 28 pacientes trabalhavam no setor de agricultura. Dos pacientes da amostra, 33 (41,2%) apresentavam histórico pessoal de neoplasias de pele, sendo que, destes, três apresentavam diagnóstico de xeroderma pigmentoso. Quanto ao hábito de uso de fatores de proteção solar, 61% (n=49) da amostra negou o hábito. Foi evidenciada associação estatisticamente significativa entre o hábito de usar fatores de proteção solar e histórico pessoal de neoplasias de pele. Em relação ao tipo de neoplasia escamosa, a maioria dos pacientes (72; 90%) apresentou diagnóstico anatomopatológico de carcinoma espinocelular ocular. Conclusão O perfil clínico epidemiológico dos pacientes portadores de neoplasias escamosas da superfície ocular neste estudo, predominantemente de carcinoma espinoceular ocular, foi de homens, idosos, de pele clara (fototipo 2) e com histórico importante de exposição aos raios solares ultravioleta A e B. Comorbidades imunodepressoras (HIV e transplante de órgão sólido) e doenças dermatológicas (albinismo e xeroderma pigmentoso) associaram-se ao aparecimento das neoplasias escamosas da superfície ocular em idade mais precoce. Em pacientes com histórico pessoal prévio de neoplasias de pele, foi evidenciado o hábito de uso de fatores de protetor solar mais presente em relação aos demais.


ABSTRACT Objective To analyze the clinical profile of patients with ocular surface squamous neoplasms (OSSN). Methods The main risk factors involved in the genesis of the ocular surface squamous neoplasms, the clinical features, and the behavioral habits associated were evaluated. This historical cohort study included 80 patients with anatomopathological diagnosis of OSSN who were treated between 2010-2020 at a reference hospital in oculoplastic and anterior segment in Santa Catarina. The clinical data and outcomes were evalated through the analysis of medical records and interviews, being later tabulated in Excel and analyzed using the SPSS 16 software. Results Regarding the clinical profile of the patients in the sample, 73.8% (n = 59) were male. The mean age of the sample was 62 years old. As for the skin phototype, according to the Fitzpatrick scale, most of the sample presented the phototype 1 and 2 (27.5% n = 22; and 55% n = 44 respectively). Regarding occupational exposure to the sun / radiation, 48% (n = 60) had history of occupational exposure, and of these, 28 patients worked in the agricultural area. Of the patients of the sample, 33 (41.2%) had a personal history of skin neoplasms, and of these, 3 had diagnosis of xeroderma pigmentosum. As for the habit of using sun protection factors, 61% (n = 49) of the sample denied the habit. A statistically significant association was evidenced between the habit of using sun protection factors and people's history of skin cancer. Regarding the type of squamous neoplasia, most patients in the 90% sample (n = 72) had an anatomopathological diagnosis of ocular squamous cell carcinoma. Conclusion The clinical epidemiological profile of patients with OSSN in this study, predominantly ocular squamous cell carcinoma, was men, elderly, fair-skinned (phototype 2) and with an important history of exposure to UVA and UVB rays. Immunosuppressive comorbidities (HIV, solid organ transplant) and dermatological diseases (albinism, xeroderma pigmentosum) are associated with the appearance of OSSN at an early age. In patients with a previous personal history of skin neoplasms, the habit of using sunscreen factors was more present than in the other patients.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Neoplasias Cutâneas/epidemiologia , Carcinoma de Células Escamosas/epidemiologia , Neoplasias da Túnica Conjuntiva/epidemiologia , Neoplasias Oculares/epidemiologia , Neoplasias Cutâneas/patologia , Luz Solar/efeitos adversos , Protetores Solares , Raios Ultravioleta/efeitos adversos , Carcinoma de Células Escamosas/patologia , Comorbidade , Inquéritos e Questionários , Fatores de Risco , Estudos de Coortes , Exposição Ocupacional , Neoplasias da Túnica Conjuntiva/patologia , Radiação Solar , Exposição Ambiental , Neoplasias Oculares/patologia , Fator de Proteção Solar/estatística & dados numéricos
4.
J. vasc. bras ; 20: e20210003, 2021. graf
Artigo em Inglês | LILACS | ID: biblio-1279378

RESUMO

Abstract Chronic ulcerations of the lower extremities are quite a common condition amongst adults, most often caused by chronic venous insufficiency. Irrespective of the main underlying cause, chronic limb ulcerations are usually associated with significant symptoms, impairing daily functioning. Improper or delayed diagnosis and inadequate treatment increase the risk of serious complications, including limb amputations. Malignancies can develop secondary to chronic leg ulcers. About 2.4% of ulcers arising from chronic venous stasis undergo malignant transformation. Squamous cell carcinoma is the most common type of malignancy found in chronic leg ulceration biopsies. Basal cell carcinoma, sarcoma, and melanoma have all been documented infrequently. In the case described here, we found lymphoma of the marginal zone of mucosa-associated lymphoid tissue (MALT), which is an extremely rare cutaneous neoplasm of the lower extremities, but one that may have an association with autoimmune diseases.


Resumo Úlceras crônicas dos membros inferiores são uma condição bastante comum entre adultos, na maioria das vezes causadas por insuficiência venosa crônica. Independente da sua causa principal, úlceras crônicas dos membros estão geralmente associadas a sintomas significativos, prejudicando o funcionamento diário. O diagnóstico inadequado ou tardio e o tratamento inadequado aumentam o risco de complicações graves, inclusive o risco de amputação do membro. Malignidades podem se desenvolver secundariamente em úlceras crônicas da perna. Em torno de 2,4% das úlceras decorrentes de estase venosa crônica sofrem transformação maligna. O carcinoma de células escomosas é o tipo de malignidade mais comum que pode ser encontrada em biópsias de úlceras crônicas da perna. Carcinoma basocelular, sarcoma e melanoma foram raramente documentados. No caso aqui descrito, encontramos linfoma da zona marginal do tecido linfoide associado à mucosa (mucosa-associated lymphoid tissue, MALT), o qual é uma neoplasia cutânea dos membros inferiores extremamente rara mas que pode estar associada a doenças autoimunes.


Assuntos
Humanos , Feminino , Idoso , Insuficiência Venosa/complicações , Síndrome de Sjogren/complicações , Linfoma de Zona Marginal Tipo Células B/complicações , Neoplasias Cutâneas , Úlcera , Doença Crônica , Linfoma de Zona Marginal Tipo Células B/diagnóstico , Perna (Membro)
5.
An. bras. dermatol ; 95(5): 583-588, Sept.-Oct. 2020. tab
Artigo em Inglês | LILACS, ColecionaSUS | ID: biblio-1130933

RESUMO

Abstract Background: High-risk basal cell carcinoma involves a significant rate of basal cell carcinoma that requires Mohs micrographic surgery for definitive treatment. Staged excision with pathologic margin control is a simple, accessible, and curative procedure suggested for the treatment of high-risk basal cell carcinoma. Objective: To evaluate the results of staged excision of high-risk basal cell carcinoma in the head region. Methods: This interventional study was performed on patients with high-risk basal cell carcinoma, who underwent staged excision until the margins were free of tumor. Results: A total of 122 patients (47 females and 75 males) with mean age of 57.66 ± 9.13 years were recruited in this study. Nasal and nodular types were the most common of both clinical and pathologic forms, respectively. Further, 89.3 % of cases were cured by staged excision after four years of follow-up. There was a significant relationship between treatment outcomes and recurrent lesions, multiplicity of risk factors, long-standing disease, and pathologic type. There was also a significant association between the number of surgical excisions and multiplicity of risk factors, as well as recurrence, location, and size of basal cell carcinoma. Study limitations: Lack of magnetic resonance imaging assessment in cases of suspected perineural invasion. Conclusions: High-risk basal cell carcinoma had a high cure rate by staged excision. Patients with more risk factors and those with nasal and recurrent basal cell carcinoma required more staged excisions. Failure of treatment is more probable in patients with more risk factors, long-standing lesions, and high-risk pathologic and recurrent basal cell carcinomas.


Assuntos
Humanos , Masculino , Feminino , Idoso , Neoplasias Cutâneas/cirurgia , Carcinoma Basocelular , Neoplasias de Cabeça e Pescoço/cirurgia , Cirurgia de Mohs , Resultado do Tratamento , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/cirurgia
6.
An. bras. dermatol ; 94(3): 313-319, May-June 2019. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1011106

RESUMO

Abstract: Background: Actinic keratosis (AK) represents a risk of progression to squamous cell carcinoma. Ingenol mebutate gel is a novel therapeutic option for field-directed treatment. Objectives: To evaluate the safety, tolerability and patients' perspectives, related to the therapeutic success of managing AKs on the face and scalp with ingenol mebutate gel in Brazilian individuals. Methods: This was an observational, retrospective and descriptive study of 68 areas of actinic keratosis on the face and scalp treated with Ingenol mebutate gel involving a total of 37 patients. The drug was applied for three consecutive days on an area of of 25 cm2 and documentation was performed on baseline and days 4, 8, 15, 60 and 180. On day 4, the composite local skin reaction score was calculated. At the end, a questionnaire was applied to evaluate patients' perspectives about the treatment. Results: Adherence was 100%, no serious adverse events were recorded and the mean composite local skin reaction score (standard deviation) was 8.61±4.22. The treatment was considered optimum by 75.68% of the patients. Study limitations: Calculation of composite local skin reaction score performed only on the fourth day. Conclusions: Treatment with ingenol mebutate gel was considered safe and tolerable in Brazilian subjects. Patients had a maximum adherence rate and a great improvement in self-esteem. The results of this research reproduce the findings of the literature.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Fármacos Dermatológicos/uso terapêutico , Diterpenos/uso terapêutico , Ceratose Actínica/tratamento farmacológico , Géis/uso terapêutico , Dermatoses do Couro Cabeludo/tratamento farmacológico , Administração Cutânea , Brasil , Inquéritos e Questionários , Estudos Retrospectivos , Resultado do Tratamento , Dermatoses Faciais/tratamento farmacológico
7.
An. bras. dermatol ; 93(4): 529-534, July-Aug. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-949909

RESUMO

Abstract: Background: Actinic keratoses are benign intraepithelial skin neoplasms that develop in photoexposed areas and can progress to invasive carcinoma. They are seen frequently in dermatological practice, occurring in 5.1% of consultations. Ingenol mebutate (IM) was recently approved in Brazil as a topical therapy for field cancerization in actinic keratosis. Objective: To evaluate the clearance rate and adverse events in the treatment of actinic keratoses with ingenol mebutate. Methods: A longitudinal, prospective, non-randomized, interventional, open, single-center study was conducted. Patients with actinic keratoses applied ingenol mebutate on a 25cm2 area of the face and/or scalp for three consecutive days (0.015%) or on the forearm for two days (0.05%). Results: 27 patients completed the protocol, of whom 13 on the face and/or scalp and 14 on the forearm. Complete clearance occurred in 53.8% in the first group and 42.8% in the second. Partial response was observed in 15.4% and 35.7%, respectively. The most common side effects were erythema, edema, desquamation, pruritus, and local erosion. Study limitations: The study had a small sample and was not randomized, double-blind, placebo-controlled, or vehicle-controlled. Conclusion: Ingenol mebutate is well-tolerated for the treatment of actinic keratosis, with good patient adherence thanks to the short treatment period.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Diterpenos/uso terapêutico , Ceratose Actínica/tratamento farmacológico , Método Duplo-Cego , Estudos Prospectivos , Estudos Longitudinais , Resultado do Tratamento , Diterpenos/efeitos adversos , Diterpenos/farmacocinética , Ceratose Actínica/metabolismo
8.
An. bras. dermatol ; 92(6): 882-884, Nov.-Dec. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1038258

RESUMO

Abstract: Basal cell carcinoma and Squamous cell carcinoma, referred to as non-melanoma skin cancer, are the most common malignancies in humans. Their incidence is increasing worldwide every year. In Brazil, even with the advent of educational campaigns on photoprotection and laws that banned tanning beds, they are the most frequent neoplasias, representing a public health problem recognized by the Ministry of health.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Neoplasias Cutâneas/epidemiologia , Carcinoma Basocelular/epidemiologia , Carcinoma de Células Escamosas/epidemiologia , Instituições de Assistência Ambulatorial/estatística & dados numéricos , Hospitais Públicos/estatística & dados numéricos , Brasil/epidemiologia , Comorbidade , Distribuição por Sexo , Distribuição por Idade
9.
An. bras. dermatol ; 92(5): 638-641, Sept.-Oct. 2017. tab
Artigo em Inglês | LILACS | ID: biblio-887038

RESUMO

Abstract: Background: Immunosuppressive therapy, which is necessary to avoid graft rejection in renal transplant recipients, presents an increased risk of several pathologies, namely infectious and neoplastic. Objectives: To identify the most frequent skin diseases and their clinical and demographical risk factors within a population of renal transplant recipients. Methods: A retrospective study of renal transplant recipients referred to dermatology visit and observed for the first time from January 2008 to December 2014. Results: The study included 197 patients, 120 men (60,9%). Mean age was 50,7 years (±13,4). 12 patients (6,1%) had previous skin cancer. Infections were the most frequent reason of referral (93/197; 44%). From the total referred, 18,3% (36/197) presented pre-cancerous lesions. Malignancy was diagnosed in 36 patients (18,3%), with 29 non-melanoma skin cancers (14,7%) and 7 Kaposi sarcomas (3,6%). Ratio of basal cell carcinoma to squamous cell carcinoma was 1,1:1. Non-melanoma skin cancer was significantly associated with older age (p = 0,002), male gender (p = 0,028), history of previous skin cancer (p = 0,002) and higher duration of immunosuppressive therapy (p<0,001). Study limitations: Retrospective study, with data from the first visit in dermatology. We didn't made classification on skin-types. Conclusions: The great incidence of cutaneous infections and skin cancer is responsible for a significant morbidity. It is important to assure the regular dermatological follow-up of renal transplant recipients, which will promote the prevention, an early diagnosis and an efficient treatment.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Adulto Jovem , Dermatopatias/etiologia , Terapia de Imunossupressão/efeitos adversos , Transplante de Rim , Dermatopatias/imunologia , Neoplasias Cutâneas/etiologia , Neoplasias Cutâneas/imunologia , Fatores Socioeconômicos , Estudos Retrospectivos , Fatores de Risco , Terapia de Imunossupressão/métodos
10.
An. bras. dermatol ; 92(2): 226-230, Mar.-Apr. 2017. tab, graf
Artigo em Inglês | LILACS | ID: biblio-838043

RESUMO

Abstract: Basal cell carcinoma is the most common skin cancer in the world. The aim of this study was to evaluate the surgical margin of basal cell carcinoma and correlate this with its histologic subtype. A retrospective analysis of pathology laboratory records from 1990 to 2000 was performed and the following data was collected: age, sex, race, anatomical location, histological type, and state of the excision margins in 1,428 histopathological reports of basal cell carcinoma. Ages ranged from 6 to 99 years, with an average of 57. There was a slight predominance of lesions in white women patients, and the most common histological subtype was the nodular, followed by the superficial. The most common locations were in the head and neck, with highest prevalence appeared in the nose. Surgical margins revealed a lateral involvement of 20.14% and a deep involvement of 12.47%. The fibrosing basal cell carcinoma is the histological type that most often presented positive surgical margins.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Adulto Jovem , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/patologia , Carcinoma Basocelular/cirurgia , Carcinoma Basocelular/patologia , Margens de Excisão , Recidiva , Estudos Retrospectivos , Fatores de Risco
11.
An. bras. dermatol ; 91(6): 764-769, Nov.-Dec. 2016. tab, graf
Artigo em Inglês | LILACS | ID: biblio-837998

RESUMO

Abstract BACKGROUND: Dermatoscopy is a non-invasive diagnostic tool used to examine skin lesions with an optical magnification. It has been suggested as a useful tool for monitoring therapeutic response in lentigo maligna patients treated with imiquimod. OBJECTIVE: To examine the accuracy of dermatoscopy as a tool to monitor the therapeutic response of pigmented basal cell carcinoma treated with imiquimod. METHOD: The authors designed a prospective study. Patients with pigmented basal cell carcinoma were included and data regarding the dermatoscopy features were collected following the Menzies criteria, prior to initiating the imiquimod treatment. Subsequent dermatoscopic evaluations were performed at weeks 4 and 8, following imiquimod discontinuation. RESULTS: Twenty lesions were included. The most common pigmented dermatoscopy features were large blue-grey ovoid nests (80%), followed by blue-grey globules (50%) and leaf-like areas (30%). No spoke wheel areas were observed. In 17 out of 20 patients, a response was noted during the first evaluation at 4 weeks, while the clearance was noted at the second check-up after 8 weeks. In two patients, the clearance was found at the initial evaluation at 4 weeks, while in one patient, the response remained unchanged. Blue-grey globules were the fastest to exhibit clearance (50% at week 4), followed by leaf-like areas (15%) and large blue-grey ovoid nests (6.25%). CONCLUSION: According to our results, dermatoscopic evaluation enhances the accuracy in the assessment of the clinical response to imiquimod in pigmented basal cell carcinoma.


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Neoplasias Cutâneas/diagnóstico por imagem , Carcinoma Basocelular/tratamento farmacológico , Carcinoma Basocelular/diagnóstico por imagem , Dermoscopia/métodos , Aminoquinolinas/uso terapêutico , Antineoplásicos/uso terapêutico , Transtornos da Pigmentação/patologia , Transtornos da Pigmentação/tratamento farmacológico , Transtornos da Pigmentação/diagnóstico por imagem , Pele/patologia , Neoplasias Cutâneas/patologia , Fatores de Tempo , Carcinoma Basocelular/patologia , Estudos Prospectivos , Reprodutibilidade dos Testes , Resultado do Tratamento
12.
An. bras. dermatol ; 91(5,supl.1): 140-143, Sept.-Oct. 2016. graf
Artigo em Inglês | LILACS | ID: biblio-837938

RESUMO

Abstract The paramedian forehead flap is a great option for restoration of complex nasal defects. For full-thickness defects, it may be used alone or in combination with other methods. We present a patient with a basal cell carcinoma on the distal nose treated by Mohs micrographic surgery, and a resulting full-thickness defect repaired with paramedian forehead flap combined with a hinge flap. For optimal results with the paramedian forehead flap, adequate surgical planning, patient orientation and meticulous surgical technique are imperative.


Assuntos
Humanos , Masculino , Idoso , Neoplasias Cutâneas/cirurgia , Retalhos Cirúrgicos , Carcinoma Basocelular/cirurgia , Neoplasias Nasais/cirurgia , Cirurgia de Mohs/métodos , Fatores de Tempo , Cartilagem/cirurgia , Nariz/cirurgia , Reprodutibilidade dos Testes , Resultado do Tratamento , Testa
13.
Rev. bras. cir. plást ; 31(4): 474-480, 2016. ilus, tab
Artigo em Inglês, Português | LILACS | ID: biblio-827430

RESUMO

Introduction: Reconstruction of complex facial defects is a challenge to the plastic surgeon. Different missing anatomical units must be accessed in different ways and with individualized goals, always tailoring the options to the patient's needs. The objective is to examine the role of the mid-forehead flap in the reconstruction of different anatomical facial units. Methods: Retrospective analysis of patients who were operated on by the author from February 2010 to June 2015. Patients were evaluated according to age, sex, lesion etiology, defect location, number of operations performed per patient, and postoperative complications. Results: Fifteen patients (mean age, 69 years) underwent facial reconstruction with a mid-forehead flap. Thirteen patients required more than one operation for pedicle refinement and transection. There was one case of partial necrosis of the flap in the columella region, with satisfactory healing by second intention. There was no infection or hematoma. All secondary cartilage grafts showed integration into the recipient bed. Conclusions: The mid-forehead flap remains an important tool for the reconstruction of major facial defects. It allows the transfer of frontal tissue in an efficient and reliable way with minimal deformity in the donor area, resulting in an esthetically acceptable reconstruction.


Introdução: A reconstrução de defeitos complexos faciais é um desafio ao cirurgião plástico. Diferentes unidades anatômicas ausentes devem ser acessadas de maneiras distintas e com objetivos próprios, sempre adequando as possibilidades ao paciente em questão. O objetivo é mostrar o papel do retalho médio-frontal na reconstrução de diferentes unidades anatômicas faciais. Métodos: Análise retrospectiva de pacientes operadas pela autora, no período de fevereiro de 2010 a junho de 2015. Os pacientes foram avaliados em relação à idade, sexo, etiologia da lesão, localização do defeito, número de tempos cirúrgicos realizados por paciente e complicações pós-operatórias. Resultados: Quinze pacientes foram submetidos à reconstrução facial com retalho médiofrontal, com média de idade de 69 anos. Treze pacientes necessitaram mais de um tempo cirúrgico para refinamento e transecção do pedículo. Houve um caso de necrose parcial do retalho na região da columela, com cicatrização satisfatória por segunda intenção. Não houve infecção ou hematoma. Todos os enxertos cartilaginosos secundários se integraram ao leito receptor. Conclusões: O retalho médio-frontal permanece como importante ferramenta na reconstrução de grandes defeitos faciais. Permite a transferência de tecido frontal de forma eficiente e confiável com mínima deformidade na área doadora, possibilitando uma reconstrução esteticamente aceitável.


Assuntos
Humanos , Masculino , Feminino , Idoso , História do Século XXI , Pacientes , Neoplasias Cutâneas , Retalhos Cirúrgicos , Nariz , Registros Médicos , Estudos Retrospectivos , Procedimentos de Cirurgia Plástica , Transplantes , Face , Pacientes/psicologia , Pacientes/estatística & dados numéricos , Neoplasias Cutâneas/cirurgia , Neoplasias Cutâneas/terapia , Retalhos Cirúrgicos/cirurgia , Retalhos Cirúrgicos/efeitos adversos , Nariz/anatomia & histologia , Nariz/anormalidades , Nariz/cirurgia , Registros Médicos/normas , Procedimentos de Cirurgia Plástica/métodos , Transplantes/anatomia & histologia , Transplantes/cirurgia , Face/anatomia & histologia , Face/cirurgia
14.
An. bras. dermatol ; 90(6): 846-850, Nov.-Dec. 2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-769517

RESUMO

Abstract: BACKGROUND: Most available studies on the efficacy of topical photodynamic therapy focus on short-to medium-term results. Long-term data are scarce. OBJECTIVE: To evaluate the long-term efficacy of photodynamic therapy with topical methylaminolevulinate to treat Bowen's disease and basal cell carcinoma in the clinical practice setting of a dermato-oncology department. METHODS: The study included patients diagnosed with Bowen's disease or basal cell carcinoma, and who received photodynamic therapy from 2004 to 2008. Treatment protocol and clinical follow-up were standardized. The primary endpoint was clinically observed recurrence in a previous photodynamic therapy-treated area. Descriptive and survival analyses were performed. RESULTS: A total of 31 Bowen's disease lesions and 44 superficial basal cell carcinoma were treated, with a median follow-up of 43.5 months. Recurrence was observed in 14 Bowen's disease lesions (53.8%) and in 11 superficial basal cell carcinoma (33.3%). Significantly higher estimates for recurrence rates were found in patients with Bowen's disease (p=0.0036) or those aged under 58 years (p=0.039). The risk of recurrence was higher in patients with Bowen's disease than in those with superficial basal cell carcinoma and younger patients. CONCLUSIONS: Recurrence should be considered when choosing to treat non-melanoma skin cancer with photodynamic therapy. Younger age and Bowen's disease were independent predictors for long-term recurrence, suggesting the need to establish an extended period of follow-up for this subset of patients.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Ácido Aminolevulínico/análogos & derivados , Doença de Bowen/tratamento farmacológico , Carcinoma Basocelular/tratamento farmacológico , Recidiva Local de Neoplasia , Fotoquimioterapia/métodos , Fármacos Fotossensibilizantes/uso terapêutico , Neoplasias Cutâneas/tratamento farmacológico , Administração Cutânea , Fatores Etários , Ácido Aminolevulínico/uso terapêutico , Seguimentos , Estudos Retrospectivos , Medição de Risco , Estatísticas não Paramétricas , Fatores de Tempo , Resultado do Tratamento
15.
An. bras. dermatol ; 90(5): 638-645, tab, graf
Artigo em Inglês | LILACS | ID: lil-764418

RESUMO

AbstractBACKGROUND:Cutaneous melanoma (CM) is considered serious for causing frequent metastasis, presenting high mortality, resistance to available therapies and incidences in laboring activity.OBJECTIVES:To study the histopathological types of cutaneous melanoma in Palmas-TO from 2001 to 2011, according to risk factors, location of lesions, Clark levels and Breslow thickness.METHODS:A descriptive, retrospective and quantitative research in reports of the Serviços de Anatomia Patológica in Palmas (SAPP) and Registro de Câncer de Base Populacional de Palmas (RCBPP).RESULTS:The years of highest incidences were: 2004 (8 cases/17.8%), 2008 and 2011 (7 cases each/15.6%) and 2010 (6 cases/13.3%). Among the 45 cases studied, there were predominance in patients between 41 and 60 years old, women, caucasians, farmers, located in trunk, in situ type, superficial extensive and metastatic cutaneous, Clark levels I (20%) and IV (17.7%), Breslow thickness ≤1 mm (35.5%) and 2.01 to 4 mm (24.4%).CONCLUSIONS:The most common histopathological types were: cutaneous melanoma in situ, superficial extensive and metastatic, followed by nodular cutaneous melanoma, and finally, by other forms. In this study, Clark levels and Breslow thickness pointed to greater importance of thin melanomas and sun exposure without appropriate protection in farmers.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Melanoma/epidemiologia , Melanoma/patologia , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/patologia , Distribuição por Idade , Fatores Etários , Brasil/epidemiologia , Estadiamento de Neoplasias , Estudos Retrospectivos , Fatores de Risco , Distribuição por Sexo , Fatores Sexuais
16.
Rev. Esc. Enferm. USP ; 49(4): 564-571, July-Aug. 2015. tab
Artigo em Inglês | LILACS, BDENF | ID: lil-757477

RESUMO

OBJECTIVETo identify the exposure of rural workers to the sun's ultraviolet radiation and pesticides; to identify previous cases of skin cancer; and to implement clinical and communicative nursing actions among rural workers with a previous diagnosis of skin cancer.METHODObservational-exploratory study conducted with rural workers exposed to ultraviolet radiation and pesticides in a rural area in the extreme south of Brazil. A clinical judgment and risk communication model properly adapted was used to develop interventions among workers with a previous history of skin cancer.RESULTSA total of 123 (97.7%) workers were identified under conditions of exposure to the sun's ultraviolet radiation and pesticides; seven (5.4%) were identified with a previous diagnosis of skin cancer; four (57.1%) of these presented potential skin cancer lesions.CONCLUSIONThis study's results enabled clarifying the combination of clinical knowledge and risk communication regarding skin cancer to rural workers.


OBJETIVOIdentificar la exposición de trabajadores rurales a la radiación solar ultravioleta y los pesticidas; identificar casos anteriores de cáncer de piel y aplicar la acción clínica y comunicativa de Enfermería a los trabajadores rurales con diagnóstico anterior de cáncer de piel.MÉTODOEstudio observacional-exploratorio realizado con trabajadores rurales expuestos a la radiación solar ultravioleta y los pesticidas, en área rural en el extremo sur de Brasil. Se utilizó un modelo adaptado de juicio clínico y comunicación de riesgo para el desarrollo de intervención a los trabajadores con diagnóstico anterior de cáncer de piel.RESULTADOSSe identificaron: 123 (97,7%) trabajadores en condiciones de exposición a la radiación solar ultravioleta y los pesticidas; siete (5,4%) con diagnóstico anterior de cáncer de piel y, de esos, cuatro (57,1%) presentaron lesiones potenciales de cáncer de piel. Conclusión: Los resultados del estudio permitieron elucidar la conjugación entre el conocimiento clínico y la comunicación de riesgo de cáncer de piel para trabajadores rurales.


OBJETIVOIdentificar a exposição de trabalhadores rurais à radiação solar ultravioleta e aos pesticidas; identificar casos pregressos de câncer de pele e aplicar a ação clínica e comunicativa de Enfermagem aos trabalhadores rurais com diagnóstico pregresso de câncer de pele.MÉTODOEstudo observacional-exploratório realizado com trabalhadores rurais expostos à radiação solar ultravioleta e aos pesticidas, em área rural no extremo sul do Brasil. Utilizou-se um modelo adaptado de julgamento clínico e comunicação de risco para o desenvolvimento de intervenção aos trabalhadores com diagnóstico pregresso de câncer de pele.RESULTADOSIdentificou-se: 123 (97,7%) trabalhadores em condições de exposição à radiação solar ultravioleta e aos pesticidas; sete (5,4%) com diagnóstico pregresso de câncer de pele e desses, quatro (57,1%) apresentaram lesões potenciais de câncer de pele.CONCLUSÃOOs resultados do estudo permitiram elucidar a conjugação entre o conhecimento clínico e comunicação de risco de câncer de pele para trabalhadores rurais.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Processo de Enfermagem , Doenças Profissionais/etiologia , Praguicidas/efeitos adversos , Neoplasias Cutâneas/etiologia , Raios Ultravioleta/efeitos adversos , Exposição Ocupacional/efeitos adversos , Saúde da População Rural
17.
An. bras. dermatol ; 90(3,supl.1): 235-238, May-June 2015. ilus
Artigo em Inglês | LILACS | ID: lil-755753

RESUMO

Abstract

Eccrine syringofibroadenoma is a rare benign adnexal neoplasm derived from cells of the acrosyringium of eccrine sweat glands. ESFA usually manifests as a solitary nodule on the extremities of elderly patients, but it may also present as papules, nodules or plaques. Its clinical appearance is nonspecific and malignant neoplasms should beconsidered in the differential diagnosis. However, histopathological findings are typical. The main treatment is surgical excision. In order to illustrate a typical presentation of the tumor, we report a case of solitary eccrine syringofibroadenoma, including the surgical treatment used and its result.

.


Assuntos
Idoso de 80 Anos ou mais , Feminino , Humanos , Glândulas Écrinas/patologia , Fibroadenoma/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Siringoma/patologia , Tornozelo , Biópsia , Glândulas Écrinas/cirurgia , Fibroadenoma/cirurgia , Neoplasias das Glândulas Sudoríparas/cirurgia , Siringoma/cirurgia , Resultado do Tratamento
18.
An. bras. dermatol ; 90(3,supl.1): 36-38, May-June 2015. ilus
Artigo em Inglês | LILACS | ID: lil-755793

RESUMO

Abstract

The microcystic adnexal carcinoma is a rare, locally aggressive malignant adnexal neoplasm associated with signifi cant morbidity. It is often underdiagnosed due to clinical and histopathological resemblance with other cutaneous neoplasms and / or a combination of lack of familiarity associated with inadequate samples. We report a case with clinical hypothesis of scarring alopecia and histopathological diagnosis of microcystic adnexal carcinoma with favorable outcome in a follow-up of eleven years, after surgical treatment.

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Assuntos
Idoso , Feminino , Humanos , Alopecia/patologia , Carcinoma de Apêndice Cutâneo/patologia , Neoplasias Cutâneas/patologia , Biópsia , Carcinoma de Apêndice Cutâneo/cirurgia , Diagnóstico Diferencial , Couro Cabeludo/patologia , Neoplasias Cutâneas/cirurgia , Resultado do Tratamento
19.
An. bras. dermatol ; 90(2): 258-260, Mar-Apr/2015. graf
Artigo em Inglês | LILACS | ID: lil-741069

RESUMO

Local flaps are the standard procedure to reconstruct facial defects. As it occurs in any surgical procedure, the incision should be planned so that scars are located in the minimum skin tension lines. We report two cases of O to Z flaps in the supra and infraciliary regions. One of them is a hatchet flap.


Assuntos
Humanos , Masculino , Feminino , Adulto , Idoso , Retalhos Cirúrgicos , Neoplasias Faciais/cirurgia , Carcinoma/cirurgia , Nevo Sebáceo de Jadassohn/cirurgia , Procedimentos Cirúrgicos Dermatológicos/métodos , Resultado do Tratamento , Face/cirurgia
20.
An. bras. dermatol ; 90(2): 202-210, Mar-Apr/2015. tab
Artigo em Inglês | LILACS | ID: lil-741065

RESUMO

BACKGROUND: Telemedicine refers to the use of technology as improvement of healthcare delivery to places where distance becomes an obstacle. Its use represents a great potential for dermatology, a specialty whose visual analysis phase is essential in diagnosis. OBJECTIVES: To analyze the compatibility index of skin cancer diagnoses between primary care and teledermatology, and to validate a protocol for standardization of digital imaging to obtain the reports in teledermatology. METHODS: An observational cross-sectional study developed through the census of 333 examination requests, received between January/2012 and July/2012, in the Center for Telemedicine and Telehealth of SES-SC. We used a protocol for photographic lesion standardization, consisting of three steps (panoramic photo, close-up with ruler and dermoscopy). After collection, the data were sent to a virtual site on the Internet, and recorded with the use of an electronic health record containing the images, the skin phototype and demographic characteristics. RESULTS: The level of compatibility between the diagnosis of skin cancer in Santa Catarina's primary care and the diagnosis proposed by teledermatology was 19.02%. Proportionally, it was 21.21% for BCC, 44.44% for SCC and 6.98% for MM. The protocol was statistically significant (p <0.05), with an OR of 38.77. CONCLUSION: The rate of diagnostic compatibility of skin cancer was low and the use of the protocol optimized the chance of validating requests for examination. .


Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Dermatologia/normas , Interpretação de Imagem Assistida por Computador/normas , Atenção Primária à Saúde/normas , Neoplasias Cutâneas/diagnóstico , Telemedicina/normas , Estudos Transversais , Dermatologia/métodos , Variações Dependentes do Observador , Valor Preditivo dos Testes , Atenção Primária à Saúde/métodos , Reprodutibilidade dos Testes , Telemedicina/métodos , Telepatologia/métodos , Telepatologia/normas
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